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Structure–activity relationships study of mTOR kinase inhibition using QSAR and structure-based drug design approaches
The discovery of clinically relevant inhibitors of mammalian target of rapamycin (mTOR) for anticancer therapy has proved to be a challenging task. The quantitative structure–activity relationship (QSAR) approach is a very useful and widespread technique for ligand-based drug design, which can be us...
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| 出版年: | Onco Targets Ther |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144904/ https://ncbi.nlm.nih.gov/pubmed/27980424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S108526 |
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