A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis

Angiogenesis is a major therapeutic target. Ideal drug targets are genes expressed only in endothelial cells (ECs) or only during the angiogenic process. Here, we describe a gene, p73RhoGAP (p73), that has both of these properties. By using a PCR-based subtraction–hybridization approach to clone cDN...

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Bibliographische Detailangaben
Hauptverfasser: Su, Zhi-Jian, Hahn, Christopher N., Goodall, Gregory J., Reck, Niamh M., Leske, Annabell F., Davy, Ann, Kremmidiotis, Gabriel, Vadas, Mathew A., Gamble, Jennifer R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514459/
https://ncbi.nlm.nih.gov/pubmed/15302923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404631101
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