The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells

RhoGTPases are important regulators of the cell cytoskeleton, controlling cell shape, migration and proliferation. Previously we showed that ARHGAP18 in endothelial cells is important in cell junctions. Here we show, using structured illumination microscopy (SIM), ground-state depletion (GSD), and t...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Lovelace, Michael D., Powter, Elizabeth E., Coleman, Paul R., Zhao, Yang, Parker, Amelia, Chang, Garry H., Lay, Angelina J., Hunter, Julie, McGrath, Aaron P., Jormakka, Mika, Bertolino, Patrick, McCaughan, Geoffrey, Kavallaris, Maria, Vadas, Mathew A., Gamble, Jennifer R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391183/
https://ncbi.nlm.nih.gov/pubmed/28251925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-05-0285
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