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YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress
The tumor suppressor p53 regulates cell-cycle progression and apoptosis in response to genotoxic stress, and inactivation of p53 is a common feature of cancer cells. The levels and activity of p53 are tightly regulated by posttranslational modifications, including phosphorylation, ubiquitination, an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514451/ https://ncbi.nlm.nih.gov/pubmed/15295102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402283101 |
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