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A Proinflammatory Cytokine Inhibits P53 Tumor Suppressor Activity

p53 has a key role in the negative regulation of cell proliferation, in the maintenance of genomic stability, and in the suppression of transformation and tumorigenesis. To identify novel regulators of p53, we undertook two functional screens to isolate genes which bypassed either p53-mediated growt...

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Detalhes bibliográficos
Main Authors: Hudson, James D., Shoaibi, Mahmood A., Maestro, Roberta, Carnero, Amancio, Hannon, Gregory J., Beach, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195698/
https://ncbi.nlm.nih.gov/pubmed/10562313
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