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Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT(2C) receptor mediated appetite
Alternate splicing of serotonin (5-hydroxytryptamine; 5-HT) 2C receptor (5-HT(2C)R) pre-RNA is negatively regulated by the small nucleolar RNA, Snord115, loss of which is observed in nearly all individuals with Prader-Willi Syndrome (PWS), a multigenic disorder characterised by hyperphagia and obesi...
Zapisane w:
| Wydane w: | Mol Brain |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5144496/ https://ncbi.nlm.nih.gov/pubmed/27931246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0277-4 |
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