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A nucleophile-catalyzed cycloisomerization permits a concise synthesis of (+)-harziphilone

Substantial structural transformations of much use in complex chemical synthesis can be achieved by channeling the reactivity of highly unsaturated molecules. This report describes the direct conversion of an acyclic polyunsaturated diketone to the HIV-1 Rev/Rev-responsive element inhibitor harziphi...

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Detalhes bibliográficos
Main Authors: Stark, Lucy M., Pekari, Klaus, Sorensen, Erik J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514435/
https://ncbi.nlm.nih.gov/pubmed/15232001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402563101
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