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A unified approach to the tedanolides: Total synthesis of (+)-13-deoxytedanolide

A unified approach for the construction of the potent marine antitumor agents (+)-tedanolide (1) and (+)-13-deoxytedanolide (2) is described. Highlights of the synthetic strategy include the development of a versatile bifunctional dithiane-vinyl iodide linchpin, the unorthodox use of the Evans–Tishc...

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Hlavní autoři: Smith, Amos B., Adams, Christopher M., Barbosa, Stephanie A. Lodise, Degnan, Andrew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC514431/
https://ncbi.nlm.nih.gov/pubmed/15163795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402084101
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