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Total synthesis and structure of the ramoplanin A1 and A3 aglycons: Two minor components of the ramoplanin complex

Ramoplanin is a potent antibiotic, first disclosed in 1984, that acts by inhibiting bacterial cell-wall biosynthesis. The original ramoplanin complex was shown to consist of a mixture of three closely related compounds, ramoplanin A1–A3, of which ramoplanin A2 is the most abundant. The structure of...

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Autors principals: Shin, Dongwoo, Rew, Yosup, Boger, Dale L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514419/
https://ncbi.nlm.nih.gov/pubmed/15175429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401419101
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