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Concordance between somatic copy number loss and down-regulated expression: A pan-cancer study of cancer predisposition genes

Cancer predisposition genes (CPGs) are a class of cancer genes in which germline variants lead to increased risk of cancer. Research has revealed that copy number variation (CNV) may be linked to cancer susceptibility in CPGs. In this pan-cancer analysis, we explored the relationship between somatic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Ran, Zhao, Ming, Zheng, Chun-Hou, Zhao, Min, Xia, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144096/
https://ncbi.nlm.nih.gov/pubmed/27929028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37358
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