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Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study
BACKGROUND: Tumor suppressor genes (TSGs) encode the guardian molecules to control cell growth. The genomic alteration of TSGs may cause tumorigenesis and promote cancer progression. So far, investigators have mainly studied the functional effects of somatic single nucleotide variants in TSGs. Copy...
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| Veröffentlicht in: | BMC Genomics |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001246/ https://ncbi.nlm.nih.gov/pubmed/27556634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2904-y |
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