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Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study
BACKGROUND: Tumor suppressor genes (TSGs) encode the guardian molecules to control cell growth. The genomic alteration of TSGs may cause tumorigenesis and promote cancer progression. So far, investigators have mainly studied the functional effects of somatic single nucleotide variants in TSGs. Copy...
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| Pubblicato in: | BMC Genomics |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001246/ https://ncbi.nlm.nih.gov/pubmed/27556634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2904-y |
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