Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides

Hexitol nucleic acids (HNAs) are nuclease resistant and provide strong hybridization to RNA. However, there is relatively little information on the biological properties of HNA antisense oligonucleotides. In this study, we compared the antisense effects of a chimeric HNA ‘gapmer’ oligonucleotide com...

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Autors principals: Kang, Hyunmin, Fisher, Michael H., Xu, Dong, Miyamoto, Yuko J., Marchand, Arnaud, Van Aerschot, Arthur, Herdewijn, Piet, Juliano, Rudolph L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514393/
https://ncbi.nlm.nih.gov/pubmed/15316104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh775
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