Engineered adenovirus fiber shaft fusion homotrimer of soluble TRAIL with enhanced stability and antitumor activity

Successful cancer therapies aim to induce selective apoptosis in neoplastic cells. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered an attractive anticancer agent due to its tumor cell-specific cytotoxicity. However, earlier studies with recombinant TRAIL revealed many s...

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Vydáno v:Cell Death Dis
Hlavní autoři: Yan, J, Wang, L, Wang, Z, Wang, B, Zhu, R, Bi, J, Wu, J, Zhang, H, Wu, H, Yu, B, Kong, W, Yu, X
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143403/
https://ncbi.nlm.nih.gov/pubmed/27336718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.177
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