Mysm1 is required for interferon regulatory factor expression in maintaining HSC quiescence and thymocyte development

Mysm1(−/−) mice have severely decreased cellularity in hematopoietic organs. We previously revealed that Mysm1 knockout impairs self-renewal and lineage reconstitution of HSCs by abolishing the recruitment of key transcriptional factors to the Gfi-1 locus, an intrinsic regulator of HSC function. The...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Huang, X F, Nandakumar, V, Tumurkhuu, G, Wang, T, jiang, X, Hong, B, Jones, L, Won, H, Yoshii, H, Ozato, K, Masumi, A, Chen, S-Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143390/
https://ncbi.nlm.nih.gov/pubmed/27277682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.162
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars