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Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death

Transglutaminase 2 (TG2) is primarily known as the most ubiquitously expressed member of the transglutaminase family with Ca(2+)-dependent protein crosslinking activity; however, this enzyme exhibits multiple additional functions through GTPase, cell adhesion, protein disulfide isomerase, kinase, an...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Tatsukawa, H, Furutani, Y, Hitomi, K, Kojima, S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143380/
https://ncbi.nlm.nih.gov/pubmed/27253408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.150
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