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The Calpain/Calpastatin System Has Opposing Roles in Growth and Metastatic Dissemination of Melanoma

Conventional calpains are ubiquitous cysteine proteases whose activity is promoted by calcium signaling and specifically limited by calpastatin. Calpain expression has been shown to be increased in human malignant cells, but the contribution of the calpain/calpastatin system in tumorigenesis remains...

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Autores principales: Raimbourg, Quentin, Perez, Joëlle, Vandermeersch, Sophie, Prignon, Aurélie, Hanouna, Guillaume, Haymann, Jean-Philippe, Baud, Laurent, Letavernier, Emmanuel
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614974/
https://ncbi.nlm.nih.gov/pubmed/23565252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060469
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