Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function

The presence of tangles composed of phosphorylated tau is one of the neuropathological hallmarks of Alzheimer's disease (AD). Tau, a microtubule (MT)-associated protein, accumulates in AD potentially as a result of posttranslational modifications, such as hyperphosphorylation and conformational...

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Detalhes bibliográficos
Main Authors: Kim, B M, You, M-H, Chen, C-H, Lee, S, Hong, Y, Kimchi, A, Zhou, X Z, Lee, T H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047864/
https://ncbi.nlm.nih.gov/pubmed/24853415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.216
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