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Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function
The presence of tangles composed of phosphorylated tau is one of the neuropathological hallmarks of Alzheimer's disease (AD). Tau, a microtubule (MT)-associated protein, accumulates in AD potentially as a result of posttranslational modifications, such as hyperphosphorylation and conformational...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047864/ https://ncbi.nlm.nih.gov/pubmed/24853415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.216 |
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