MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies

INTRODUCTION: The MAPT H1 haplotype has been associated with several neurodegenerative diseases. We were interested in exploring the role of MAPT haplotypic variation in risk of Dementia with Lewy bodies (DLB). METHOD: We genotyped six MAPT haplotype tagging SNPs and screened 431 clinical DLB cases,...

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Pubblicato in:Alzheimers Dement
Autori principali: Labbé, Catherine, Heckman, Michael G., Lorenzo-Betancor, Oswaldo, Soto-Ortolaza, Alexandra I., Walton, Ronald L., Murray, Melissa E., Allen, Mariet, Uitti, Ryan J., Wszolek, Zbigniew K., Smith, Glenn E., Kantarci, Kejal, Knopman, David S., Lowe, Val J., Jack, Clifford R., Ertekin-Taner, Nilüfer, Hassan, Anhar, Savica, Rodolfo, Petersen, Ronald C., Parisi, Joseph E., Maraganore, Demetrius M., Graff-Radford, Neill R., Ferman, Tanis J., Boeve, Bradley F., Dickson, Dennis W., Ross, Owen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143206/
https://ncbi.nlm.nih.gov/pubmed/27287057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.05.002
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