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Structure-Based Design of Broadly Protective Group A Streptococcal M Protein-Based Vaccines
BACKGROUND: A major obstacle to the development of broadly protective M protein-based group A streptococcal (GAS) vaccines is the variability within the N-terminal epitopes that evoke potent bactericidal antibodies. The concept of M type-specific protective immune responses has recently been challen...
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| Publicado no: | Vaccine |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5143202/ https://ncbi.nlm.nih.gov/pubmed/27890396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.11.065 |
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