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Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation

Transplantation of allogeneic organs and tissues represents a lifesaving procedure for a variety of patients affected with end-stage diseases. Although current immunosuppressive therapy prevents early acute rejection, it is associated with nephrotoxicity and increased risks for infection and neoplas...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Marino, Jose, Babiker-Mohamed, Mohamed H., Crosby-Bertorini, Patrick, Paster, Joshua T., LeGuern, Christian, Germana, Sharon, Abdi, Reza, Uehara, Mayuko, Kim, James I., Markmann, James F., Tocco, Georges, Benichou, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142759/
https://ncbi.nlm.nih.gov/pubmed/27942611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaf8759
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