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In Utero Exposure to Exosomal and B-Cell Alloantigens Lessens Alloreactivity of Recipients’ Lymphocytes Rather than Confers Allograft Tolerance

According to actively acquired tolerance, antigen exposure before full immune development in fetal or early neonatal life will cause tolerance to this specific antigen. In this study, we aimed to examine whether allogeneic tolerance could be elicited by in utero exposure to surface MHC antigens of a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chen, Jeng-Chang, Ou, Liang-Shiou, Chan, Cheng-Chi, Kuo, Ming-Ling, Tseng, Li-Yun, Chang, Hsueh-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840197/
https://ncbi.nlm.nih.gov/pubmed/29552016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00418
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