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Assessment of in vivo siRNA delivery in cancer mouse models

RNA interference (RNAi) has rapidly become a powerful tool for target discovery and therapeutics. Small interfering RNAs (siRNAs) are highly effective in mediating sequence-specific gene silencing. However, the major obstacle for using siRNAs as cancer therapeutics is their systemic delivery from th...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Hatakeyama, Hiroto, Wu, Sherry Y., Mangala, Lingegowda S., Lopez-Berestein, Gabriel, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142631/
https://ncbi.nlm.nih.gov/pubmed/26721492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3378-5_15
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