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Assessment of in vivo siRNA delivery in cancer mouse models
RNA interference (RNAi) has rapidly become a powerful tool for target discovery and therapeutics. Small interfering RNAs (siRNAs) are highly effective in mediating sequence-specific gene silencing. However, the major obstacle for using siRNAs as cancer therapeutics is their systemic delivery from th...
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| Veröffentlicht in: | Methods Mol Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142631/ https://ncbi.nlm.nih.gov/pubmed/26721492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3378-5_15 |
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