Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidemia

Candidemia is the fourth most common cause of bloodstream infection, with a high mortality rate of up to 40%. Identification of host genetic factors that confer susceptibility to candidemia may aid in designing adjunctive immunotherapeutic strategies. We hypothesized that variation in immune genes m...

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Vydáno v:Nat Commun
Hlavní autoři: Kumar, Vinod, Cheng, Shih-Chin, Johnson, Melissa D., Smeekens, Sanne P., Wojtowicz, Agnieszka, Giamarellos-Bourboulis, Evangelos, Karjalainen, Juha, Franke, Lude, Withoff, Sebo, Plantinga, Theo S., van de Veerdonk, Frank L., van der Meer, Jos W.M., Joosten, Leo A.B., Bochud, Pierre-Yves, Marchetti, Oscar, Perfect, John R., Xavier, Ramnik, Kullberg, Bart Jan, Wijmenga, Cisca, Netea, Mihai G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142444/
https://ncbi.nlm.nih.gov/pubmed/25197941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5675
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