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Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells
BACKGROUND: Neuroendocrine cells (NECs) reside adjacent to colonic stem cells (SCs) in the crypt stem cell (SC) niche, but how NECs are involved in regulation of SCs is unclear. We investigated NECs expressing somatostatin (SST) and somatostatin receptor type 1 (SSTR1) because SST inhibits intestina...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142402/ https://ncbi.nlm.nih.gov/pubmed/27927191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2969-7 |
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