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LRRK2 at the interface of autophagosomes, endosomes and lysosomes

Over the past 20 years, substantial progress has been made in identifying the underlying genetics of Parkinson’s disease (PD). Of the known genes, LRRK2 is a major genetic contributor to PD. However, the exact function of LRRK2 remains to be elucidated. In this review, we discuss how familial forms...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Roosen, Dorien A., Cookson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142374/
https://ncbi.nlm.nih.gov/pubmed/27927216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0140-1
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