Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling

BACKGROUND: Nitric oxide (NO) plays a role in a number of physiological processes including stem cell differentiation and osteogenesis. Endothelial nitric oxide synthase (eNOS), one of three NO-producing enzymes, is located in a close conformation with the caveolin-1 (CAV-1(WT)) membrane protein whi...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Bandara, Nadeeka, Gurusinghe, Saliya, Lim, Shiang Yong, Chen, Haying, Chen, Shuangfeng, Wang, Dawei, Hilbert, Bryan, Wang, Le-Xin, Strappe, Padraig
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142348/
https://ncbi.nlm.nih.gov/pubmed/27927230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0442-9
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