Minicircle DNA-mediated endothelial nitric oxide synthase gene transfer enhances angiogenic responses of bone marrow-derived mesenchymal stem cells

BACKGROUND: Non-viral-based gene modification of adult stem cells with endothelial nitric oxide synthase (eNOS) may enhance production of nitric oxide and promote angiogenesis. Nitric oxide (NO) derived from endothelial cells is a pleiotropic diffusible gas with positive effects on maintaining vascu...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Bandara, Nadeeka, Gurusinghe, Saliya, Chen, Haiying, Chen, Shuangfeng, Wang, Le-xin, Lim, Shiang Y., Strappe, Padraig
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818467/
https://ncbi.nlm.nih.gov/pubmed/27036881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0307-2
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