Tris (dibenzylideneacetone) Dipalladium: A Small-Molecule Palladium Complex Is Effective in Inducing Apoptosis in Chronic Lymphocytic Leukemia B-Cells

Here we tested impact of Tris-DBA on CLL B-cell survival. Indeed treatment of CLL B-cells with Tris-DBA induced apoptosis in a dose-dependent manner irrespective of IgVH mutational status. Further analyses suggest that Tris-DBA-induced apoptosis involves reduced expression of the anti-apoptotic prot...

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Gepubliceerd in:Leuk Lymphoma
Hoofdauteurs: Kay, Neil E., Sassoon, Traci, Secreto, Charla, Sinha, Sutapa, Shanafelt, Tait D., Ghosh, Asish K., Arbiser, Jack
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142299/
https://ncbi.nlm.nih.gov/pubmed/27189785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2016.1161186
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