Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

Autophagy and the unfolded protein response (UPR) are key cellular homeostatic mechanisms and are both involved in liver diseases, including nonalcoholic fatty liver disease (NAFLD). Although increasing but conflicting results link these mechanisms to lipid metabolism, their role and potential cross...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Kwanten, Wilhelmus J., Vandewynckel, Yves-Paul, Martinet, Wim, De Winter, Benedicte Y., Michielsen, Peter P., Van Hoof, Viviane O., Driessen, Ann, Timmermans, Jean-Pierre, Bedossa, Pierre, Van Vlierberghe, Hans, Francque, Sven M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
Schlagworte:
Liver and Biliary Tract Physiology/Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142201/
https://ncbi.nlm.nih.gov/pubmed/27514483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00418.2015
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