Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

Autophagy and the unfolded protein response (UPR) are key cellular homeostatic mechanisms and are both involved in liver diseases, including nonalcoholic fatty liver disease (NAFLD). Although increasing but conflicting results link these mechanisms to lipid metabolism, their role and potential cross...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Kwanten, Wilhelmus J., Vandewynckel, Yves-Paul, Martinet, Wim, De Winter, Benedicte Y., Michielsen, Peter P., Van Hoof, Viviane O., Driessen, Ann, Timmermans, Jean-Pierre, Bedossa, Pierre, Van Vlierberghe, Hans, Francque, Sven M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Liver and Biliary Tract Physiology/Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142201/
https://ncbi.nlm.nih.gov/pubmed/27514483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00418.2015
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