Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

Autophagy and the unfolded protein response (UPR) are key cellular homeostatic mechanisms and are both involved in liver diseases, including nonalcoholic fatty liver disease (NAFLD). Although increasing but conflicting results link these mechanisms to lipid metabolism, their role and potential cross...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Kwanten, Wilhelmus J., Vandewynckel, Yves-Paul, Martinet, Wim, De Winter, Benedicte Y., Michielsen, Peter P., Van Hoof, Viviane O., Driessen, Ann, Timmermans, Jean-Pierre, Bedossa, Pierre, Van Vlierberghe, Hans, Francque, Sven M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Liver and Biliary Tract Physiology/Pathophysiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142201/
https://ncbi.nlm.nih.gov/pubmed/27514483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00418.2015
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