A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice

Cryptosporidium is recognized as one of the main causes of childhood diarrhea worldwide. However, the current treatment for cryptosporidiosis is suboptimal. Calcium flux is essential for entry in apicomplexan parasites. Calcium-dependent protein kinases (CDPKs) are distinct from protein kinases of m...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Main Authors: Castellanos-Gonzalez, Alejandro, Sparks, Hayley, Nava, Samantha, Huang, Wenlin, Zhang, Zhongsheng, Rivas, Kasey, Hulverson, Matthew A., Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Van Voorhis, Wesley C., White, Arthur Clinton
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142094/
https://ncbi.nlm.nih.gov/pubmed/27738055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw481
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