A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice

Cryptosporidium is recognized as one of the main causes of childhood diarrhea worldwide. However, the current treatment for cryptosporidiosis is suboptimal. Calcium flux is essential for entry in apicomplexan parasites. Calcium-dependent protein kinases (CDPKs) are distinct from protein kinases of m...

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Udgivet i:J Infect Dis
Main Authors: Castellanos-Gonzalez, Alejandro, Sparks, Hayley, Nava, Samantha, Huang, Wenlin, Zhang, Zhongsheng, Rivas, Kasey, Hulverson, Matthew A., Barrett, Lynn K., Ojo, Kayode K., Fan, Erkang, Van Voorhis, Wesley C., White, Arthur Clinton
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142094/
https://ncbi.nlm.nih.gov/pubmed/27738055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw481
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