Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy

Bumped kinase inhibitors (BKIs) of Cryptosporidium parvum calcium-dependent protein kinase 1 (CpCDPK1) are leading candidates for treatment of cryptosporidiosis-associated diarrhea. Potential cardiotoxicity related to anti–human ether-à-go-go potassium channel (hERG) activity of the first-generation...

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Bibliografske podrobnosti
izdano v:J Infect Dis
Main Authors: Hulverson, Matthew A., Vinayak, Sumiti, Choi, Ryan, Schaefer, Deborah A., Castellanos-Gonzalez, Alejandro, Vidadala, Rama S. R., Brooks, Carrie F., Herbert, Gillian T., Betzer, Dana P., Whitman, Grant R., Sparks, Hayley N., Arnold, Samuel L. M., Rivas, Kasey L., Barrett, Lynn K., White, A. Clinton, Maly, Dustin J., Riggs, Michael W., Striepen, Boris, Van Voorhis, Wesley C., Ojo, Kayode K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Major Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853794/
https://ncbi.nlm.nih.gov/pubmed/28329187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix120
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