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Induction of an Immune-Protective T-Cell Repertoire With Diverse Genetic Coverage by a Novel Viral-Vectored Tuberculosis Vaccine in Humans

Background. Whether a candidate tuberculosis vaccine induces clinically relevant protective T-cell repertoires in humans will not be known until the completion of costly efficacy clinical trials. Methods. We have developed an integrated immunologic approach to investigate the clinical relevance of T...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Jeyanathan, Mangalakumari, Damjanovic, Daniela, Yao, Yushi, Bramson, Jonathan, Smaill, Fiona, Xing, Zhou
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142089/
https://ncbi.nlm.nih.gov/pubmed/27703038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw467
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