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In the loop: promoter–enhancer interactions and bioinformatics

Enhancer–promoter regulation is a fundamental mechanism underlying differential transcriptional regulation. Spatial chromatin organization brings remote enhancers in contact with target promoters in cis to regulate gene expression. There is considerable evidence for promoter–enhancer interactions (P...

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Détails bibliographiques
Publié dans:Brief Bioinform
Auteurs principaux: Mora, Antonio, Sandve, Geir Kjetil, Gabrielsen, Odd Stokke, Eskeland, Ragnhild
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142009/
https://ncbi.nlm.nih.gov/pubmed/26586731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv097
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