Connective tissue growth factor is critical for proper β-cell function and pregnancy-induced β-cell hyperplasia in adult mice

During pregnancy, maternal β-cells undergo compensatory changes, including increased β-cell mass and enhanced glucose-stimulated insulin secretion. Failure of these adaptations to occur results in gestational diabetes mellitus. The secreted protein connective tissue growth factor (CTGF) is critical...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Pasek, Raymond C., Dunn, Jennifer C., Elsakr, Joseph M., Aramandla, Mounika, Matta, Anveetha R., Gannon, Maureen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142004/
https://ncbi.nlm.nih.gov/pubmed/27460898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00194.2016
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