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Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise, and Metabolic and Excitatory Challenges
The impact of mitochondrial protein acetylation status on neuronal function and vulnerability to neurological disorders is unknown. Here we show that the mitochondrial protein deacetylase SIRT3 mediates adaptive responses of neurons to bioenergetic, oxidative and excitatory stress. Cortical neurons...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Metab |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5141613/ https://ncbi.nlm.nih.gov/pubmed/26698917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.013 |
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