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Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development

Although high amounts of reactive oxygen species (ROS) can damage cells, ROS can also play roles as second messengers, regulating diverse cellular processes. Here we report that embryonic mouse cerebral cortical neural progenitor cells (NPCs) exhibit intermittent spontaneous bursts of mitochondrial...

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Autori principali: Hou, Yan, Ouyang, Xin, Wan, Ruiqian, Cheng, Heping, Mattson, Mark P., Cheng, Aiwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479374/
https://ncbi.nlm.nih.gov/pubmed/22949407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1213
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