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Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development

Although high amounts of reactive oxygen species (ROS) can damage cells, ROS can also play roles as second messengers, regulating diverse cellular processes. Here we report that embryonic mouse cerebral cortical neural progenitor cells (NPCs) exhibit intermittent spontaneous bursts of mitochondrial...

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Bibliographische Detailangaben
Hauptverfasser: Hou, Yan, Ouyang, Xin, Wan, Ruiqian, Cheng, Heping, Mattson, Mark P., Cheng, Aiwu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479374/
https://ncbi.nlm.nih.gov/pubmed/22949407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1213
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