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NeuCode labels with parallel reaction monitoring for multiplexed, absolute protein quantification

We introduce a new method to multiplex the throughput of samples for targeted mass spectrometry analysis. The current paradigm for obtaining absolute quantification from biological samples requires spiking isotopically heavy peptide standards into light biological lysates. Because each lysate must b...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Potts, Gregory K., Voigt, Emily A., Bailey, Derek J., Westphall, Michael S., Hebert, Alexander S., Yin, John, Coon, Joshua J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141612/
https://ncbi.nlm.nih.gov/pubmed/26882330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b04773
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