NeuCode proteomics reveals Bap1 regulation of metabolism

We introduce neutron-encoded (NeuCode) amino acid labeling of mice as a strategy for multiplexed proteomic analysis in vivo. Using NeuCode we characterize an inducible knock-out mouse model of Bap1, a tumor suppressor and deubiquitinase whose in vivo roles outside of cancer are not well established....

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Publicado no:Cell Rep
Main Authors: Baughman, Joshua M., Rose, Christopher M., Kolumam, Ganesh, Webster, Joshua D., Wilkerson, Emily M., Merrill, Anna E., Rhoads, Timothy W., Noubade, Rajkumar, Katavolos, Paula, Lesch, Justin, Stapleton, Donald S., Rabaglia, Mary E., Schueler, Kathy L., Asuncion, Raymond, Domeyer, Melanie, Zavala-Solorio, Jose, Reich, Michael, DeVoss, Jason, Keller, Mark P., Attie, Alan D., Hebert, Alexander S., Westphall, Michael S., Coon, Joshua J., Kirkpatrick, Donald S., Dey, Anwesha
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546211/
https://ncbi.nlm.nih.gov/pubmed/27373151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.096
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