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Novel Concepts for Drug Hypersensitivity Based on the Use of Long-Time Scale Molecular Dynamic Simulation

The discovery that several drug hypersensitivity reactions (DHRs) are associated with specific human leukocyte antigen (HLA) alleles has attracted increasing research interest. However, the underlying mechanisms of these HLA-induced DHRs remain unclear, especially for drug-induced immediate activati...

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Detaylı Bibliyografya
Yayımlandı:J Pharm (Cairo)
Asıl Yazarlar: Murai, Takahiro, Kawashita, Norihito, Tian, Yu-Shi, Takagi, Tatsuya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141551/
https://ncbi.nlm.nih.gov/pubmed/27999707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9520361
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