PD-1/PD-L pathway inhibits M.tb-specific CD4(+) T-cell functions and phagocytosis of macrophages in active tuberculosis

The role of the PD-1/PD-L pathway in a murine model of tuberculosis remains controversial regarding viral infections and clinical tuberculosis. We conducted a case-control study to investigate the modulating role and mechanism of the PD-1/PD-L pathway in patients with active tuberculosis. Fifty-nine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shen, Lei, Gao, Yan, Liu, Yuanyuan, Zhang, Bingyan, Liu, Qianqian, Wu, Jing, Fan, Lin, Ou, Qinfang, Zhang, Wenhong, Shao, Lingyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141449/
https://ncbi.nlm.nih.gov/pubmed/27924827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38362
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