BATF Potentially Mediates Negative Regulation of PD-1/PD-Ls Pathway on T Cell Functions in Mycobacterium tuberculosis Infection

Background: Previously, we have found that blockade of PD-1/PD-Ls pathway could enhance CD4(+) T cells-mediated protective immunity in patients with active tuberculosis (ATB). However, the mechanism of PD-1/PD-Ls pathway involved in negative regulation of anti-TB immunity has been still unclear. Rec...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liu, Qianqian, Ou, Qinfang, Shen, Lei, Qiu, Chao, Zhang, Bingyan, Zhang, Wenhong, Shao, Lingyun, Gao, Yan, Chen, Zheng W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803382/
https://ncbi.nlm.nih.gov/pubmed/31681314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02430
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