Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-γ Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection

OBJECTIVE: Detailed studies of correlation between HIV-M.tb co-infection and hierarchy declines of CD8+/CD4+ T-cell counts and IFN-γ responses have not been done. We conducted case-control studies to address this issue. METHODS: 164 HIV-1-infected individuals comprised of HIV-1(+)ATB, HIV-1(+)LTB an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shao, Lingyun, Zhang, Xinyun, Gao, Yan, Xu, Yunya, Zhang, Shu, Yu, Shenglei, Weng, Xinhua, Shen, Hongbo, Chen, Zheng W., Jiang, Weimin, Zhang, Wenhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784913/
https://ncbi.nlm.nih.gov/pubmed/26959228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150941
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