Time-resolved Analysis of Proteome Dynamics by Tandem Mass Tags and Stable Isotope Labeling in Cell Culture (TMT-SILAC) Hyperplexing

Recent advances in mass spectrometry have enabled system-wide analyses of protein turnover. By globally quantifying the kinetics of protein clearance and synthesis, these methodologies can provide important insights into the regulation of the proteome under varying cellular and environmental conditi...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Welle, Kevin A., Zhang, Tian, Hryhorenko, Jennifer R., Shen, Shichen, Qu, Jun, Ghaemmaghami, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141271/
https://ncbi.nlm.nih.gov/pubmed/27765818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.063230
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