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Human Collagen Prolyl 4-Hydroxylase is Activated by Ligands for its Iron Center

Collagen is the most abundant protein in animals. The posttranslational hydroxylation of proline residues in collagen contributes greatly to its conformational stability. Deficient hydroxylation is associated with a variety of disease states, including scurvy. The hydroxylation of proline residues i...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Vasta, James D., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141248/
https://ncbi.nlm.nih.gov/pubmed/27183028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00251
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